Products
Triazol-3-amine
Synonyms:3-Amino-1,2,4-triazole;Aminotriazole;Amitrole
Chemical Property of Triazol-3-Amine
● Appearance/Colour:white powder or crystals
● Vapor Pressure:0.0295mmHg at 25°C
● Melting Point:150-153 °C(lit.)
● Refractive Index:1.739
● Boiling Point:347.243 °C at 760 mmHg
● PKA:11.14±0.20(Predicted)
● Flash Point:190.729 °C
● PSA：56.73000
● Density:1.477 g/cm3
● LogP:-0.42690
● Storage Temp.:−20°C
● Solubility.:280g/l
● Water Solubility.:280 g/L (20 ºC)
● XLogP3:-0.4
● Hydrogen Bond Donor Count:2
● Hydrogen Bond Acceptor Count:3
● Rotatable Bond Count:0
● Exact Mass:84.043596145
● Heavy Atom Count:6
● Complexity:44.8
● Transport DOT Label:Class 9
Safty Information
● Pictogram(s):
Xn,
N
● Hazard Codes:Xn,N,T
● Statements:48/22-51/53-63-40-61
● Safety Statements:13-36/37-61-45-53
Useful
Chemical Classes:Pesticides -> Herbicides, Other
Canonical SMILES:C1=NNC(=N1)N
Inhalation Risk:A nuisance-causing concentration of airborne particles can be reached on spraying.
Effects of Short Term Exposure:The substance is mildly irritating to the eyes and skin.
Effects of Long Term Exposure:Tumours have been detected in experimental animals but may not be relevant to humans.
Uses:Nonselective, foliage-applied, systemic, triazole herbicide used in uncropped land and orchards to control certain grasses and to kill annual and perennial grasses and weeds. It is also effective on poison ivy, poison oak and aquatic weeds catalase inhibitor Herbicide; plant regulator.
Detailed Introduction
Triazol-3-amine is a chemical compound that belongs to the triazole family. It is an organic compound with the molecular formula C2H6N4. Triazol-3-amine consists of a triazole ring structure containing three nitrogen atoms.
Triazol-3-amine can be prepared through various synthetic routes, including the condensation reaction between an amine and a carbonyl compound in the presence of a suitable catalyst. It is a versatile building block in organic synthesis and finds applications in medicinal chemistry, agricultural chemistry, and materials science.
In medicinal chemistry, triazol-3-amine derivatives have shown promising biological activities, including antimicrobial, anticancer, and antifungal properties. They are often used as scaffolds for the synthesis of pharmaceutical agents due to their unique structural features.
In agricultural chemistry, the use of triazol-3-amine-based compounds as fungicides has gained significant attention. These compounds have demonstrated excellent efficacy against a wide range of plant diseases caused by fungi. They act by inhibiting the growth and reproduction of fungal pathogens, thereby protecting crops and promoting healthy plant growth.
Furthermore, triazol-3-amine derivatives have also been explored for their potential applications in materials science. They can be modified to possess certain desirable properties, such as thermal stability, electrical conductivity, and optical activity. This makes them suitable for the development of advanced materials, such as sensors, polymers, and catalysts.
In summary, triazol-3-amine is a versatile compound with diverse applications in various fields. Its unique structural characteristics and potential biological activities make it a valuable building block for the synthesis of pharmaceuticals, fungicides, and advanced materials. Ongoing research in this area aims to further explore the potential of triazol-3-amine and its derivatives for various applications in science and technology.
Application
Triazol-3-amine has various applications in different fields. Some of its notable applications include:
Medicinal Chemistry: Triazol-3-amine derivatives have shown potential in medicinal chemistry. They can be used as building blocks in the synthesis of pharmaceutical agents with various biological activities, including antimicrobial, anticancer, and antifungal properties. These derivatives can be modified to enhance their efficacy and selectivity against specific diseases.
Agriculture: Triazol-3-amine-based compounds have been studied for their use as fungicides in agricultural applications. They have demonstrated excellent effectiveness against fungal pathogens that can cause diseases in crops. These compounds help protect plants from infections and promote healthy plant growth.
Materials Science: Triazol-3-amine derivatives can be modified to possess desirable properties, making them suitable for various applications in materials science. They can be used as building blocks for the synthesis of advanced materials, such as sensors, polymers, and catalysts. These materials can have improved thermal stability, electrical conductivity, and optical properties.
Drug Delivery Systems: Triazol-3-amine derivatives can be used in the design and development of drug delivery systems. Their unique structure and functional groups make them suitable for the attachment of drugs, targeting ligands, or other therapeutic agents. This enables controlled and targeted delivery of drugs to specific sites in the body, improving their effectiveness and reducing side effects.
Organic Synthesis: Triazol-3-amine can serve as a versatile building block for the synthesis of various organic compounds. It can be used in the construction of complex molecules or as a precursor for the synthesis of other valuable compounds. Its reactivity and ability to form bonds with other functional groups make it a useful tool in organic synthesis.
Overall, triazol-3-amine offers a wide range of applications in medicinal chemistry, agriculture, materials science, drug delivery systems, and organic synthesis. Ongoing research and development continue to explore its potential and discover new applications for this compound.
