Products
1-Phenylurea
Synonyms:amino-N-phenylamide;N-phenylurea;urea, N-phenyl-;urea, phenyl-
Chemical Property of 1-Phenylurea
● Appearance/Colour:off-white powder
● Melting Point:145-147 °C(lit.)
● Refractive Index:1.5769 (estimate)
● Boiling Point:238 °C
● PKA:13.37±0.50(Predicted)
● Flash Point:238°C
● PSA：55.12000
● Density:1,302 g/cm3
● LogP:1.95050
● Storage Temp.:Store below +30°C.
● Solubility.:H2O: 10 mg/mL, clear
● Water Solubility.:Soluble in water.
● XLogP3:0.8
● Hydrogen Bond Donor Count:2
● Hydrogen Bond Acceptor Count:1
● Rotatable Bond Count:1
● Exact Mass:136.063662883
● Heavy Atom Count:10
● Complexity:119
● Transport DOT Label:Poison
Safty Information
- Pictogram(s):
- Hazard Codes:Xn
- Statements:22
- Safety Statements:22-36/37-24/25
Useful
Canonical SMILES:C1=CC=C(C=C1)NC(=O)N
Uses:Phenylureas are commonly used soil-applied herbicides for control of grass and small-seeded broadleaf weeds. Phenyl urea is used in organic synthesis. It acts as an efficient ligand for palladium-catalyzed Heck and Suzuki reactions of aryl bromides and iodides
Detailed Introduction
1-Phenylurea, also known as phenylcarbonylurea or N-phenylurea, is an organic compound with the chemical formula C7H8N2O. It is a white crystalline solid that is sparingly soluble in water but soluble in organic solvents.
Phenylurea is primarily used in the field of agriculture as a plant growth regulator. It acts as a cytokinin antagonist, meaning it inhibits the action of cytokinins, which are plant hormones responsible for cell division and growth. By inhibiting cytokinins, phenylurea can regulate the growth and development of plants, leading to desirable effects such as increased branching, shorter internodes, and control of vegetative growth.
Due to its plant growth-regulating properties, phenylurea finds applications in various agricultural practices. It is used to control excessive vegetative growth in horticulture and greenhouse crops, promoting a more compact and manageable plant growth habit. Phenylurea can also be utilized to delay the senescence (aging) of fruits and vegetables, extending their shelf life.
In addition to its agricultural use, phenylurea has also shown potential in other areas. It has been studied for its antifungal and antimicrobial properties, suggesting its possible use as a fungicide or preservative. Furthermore, phenylurea derivatives have been investigated for their pharmaceutical applications, such as antitumor and antiviral activities.
It is important to note that the use of phenylurea or its derivatives in agricultural and other applications must comply with relevant regulations and guidelines to ensure its safe and effective use while minimizing potential environmental and human health risks.
Application
1-Phenylurea, also known as N-phenylurea, has various applications in different fields. Here are a few notable applications:
Plant growth regulator: 1-Phenylurea is widely used as a plant growth regulator and has been shown to promote root growth and inhibit shoot growth in plants. It can be used to control plant height and stimulate lateral branching in ornamental plants.
Herbicide synergist: 1-Phenylurea is often used as a synergist in herbicide formulations. It enhances the activity and effectiveness of herbicides by improving their absorption, translocation, and efficacy in controlling weeds.
Pharmaceutical intermediate: 1-Phenylurea is used as an intermediate compound in the synthesis of various pharmaceuticals, such as antibiotics and anticancer drugs. It serves as a building block in the production of more complex organic compounds.
Analytical reagent: 1-Phenylurea is used as an analytical reagent in chemical analysis and research laboratories. It can be employed for various purposes, including the determination of trace metal ions, analysis of organic compounds, and as a standard reference material.
Polymerization catalyst: 1-Phenylurea can act as a catalyst in certain polymerization reactions. It aids in the formation of polymers by initiating or promoting chemical reactions that lead to the synthesis of polymeric materials with desired properties.
Organic synthesis: 1-Phenylurea is widely used in organic synthesis as a reactant or reagent. It can participate in reactions such as condensation, rearrangement, and cyclization, leading to the formation of various organic compounds.
It's important to note that when using 1-Phenylurea or any chemical compound, it is essential to follow proper safety guidelines and regulations to ensure the health and environmental safety.
