Synonyms:2-[N-Cyclohexylamino]ethanesulfonic acid;CHES;N-Cyclohexyl-2-aminoethanesulfonic acid;NSC 120726;Taurine,N-cyclohexyl- (7CI,8CI);2-(Cyclohexylamino)ethanesulfonic acid;
● Appearance/Colour:white crystalline powder
● Vapor Pressure:0Pa at 25℃
● Melting Point:>300 °C
● Refractive Index:1.518
● PKA:9.3(at 25℃)
● PSA:74.78000
● Density:1.23 g/cm3
● LogP:2.26820
● Storage Temp.:Store at RT.
● Sensitive.:Hygroscopic
● Solubility.:H2O: 0.5 M at 20 °C, clear, colorless
● Water Solubility.:Soluble
● XLogP3:-1.3
● Hydrogen Bond Donor Count:1
● Hydrogen Bond Acceptor Count:3
● Rotatable Bond Count:3
● Exact Mass:207.09291458
● Heavy Atom Count:13
● Complexity:213
Canonical SMILES:C1CCC(CC1)[NH2+]CCS(=O)(=O)[O-]
Uses:Biological buffer. CHES is zwitterionic buffer useful in pH range 8.6 to 10.0.CHES is widely utilized as a buffer which is used for investigations on pH-dependent processes in enzymology. It has been shown to have an unusually high affinity for the iodoacetate binding site of liver alcohol dehydrogenase. 2-(Cyclohexylamino)ethanesulfonic acid (CHES) has been used in the preparation of dimethyl trisulfide- polysorbate 80 (DMTS-PS80) formulation.
N-Cyclohexyltaurine, also known as CHT or Cyclohexyl taurine, is a chemical compound that belongs to the class of cyclohexyl sulfonic acids. It is derived from taurine, a naturally occurring amino acid.
N-Cyclohexyltaurine is widely used as a pharmaceutical intermediate and is known to have various biological activities. It has been found to possess anti-inflammatory, neuroprotective, and antioxidant properties.In addition, N-Cyclohexyltaurine has shown potential benefits in the treatment of neurodegenerative disorders, such as Alzheimer's disease, and could potentially play a role in preventing oxidative damage to cells.However, it is important to note that further research is needed to fully understand the mechanisms of action and potential therapeutic applications of N-Cyclohexyltaurine.
N-Cyclohexyltaurine, has several useful applications:
Pharmaceutical ingredient: N-Cyclohexyltaurine is used as an ingredient in pharmaceutical formulations. It can act as a stabilizer, enhancer, or active ingredient in various medications and supplements.
Neuroprotective agent: Studies have shown that N-Cyclohexyltaurine has neuroprotective properties, meaning it can help protect and preserve brain cells from damage caused by neurodegenerative diseases or traumatic brain injuries.
Ophthalmic applications: N-Cyclohexyltaurine has been investigated for its potential use in treating eye diseases and conditions. It has demonstrated antioxidant and anti-inflammatory effects, making it a potential candidate for eye drops or ophthalmic formulations.
Antioxidant: N-Cyclohexyltaurine exhibits strong antioxidant activity, which can help neutralize harmful free radicals and prevent oxidative damage to cells and tissues. This property makes it useful in many applications that require antioxidant protection.
Hair care products: N-Cyclohexyltaurine is used in some hair care products, such as shampoos and conditioners, due to its ability to enhance hair health and prevent damage. It can help improve hair strength, reduce frizz, and protect against environmental stressors.
It is important to note that N-Cyclohexyltaurine should be used and handled according to proper safety guidelines and regulations. Additionally, specific applications and requirements may vary, so consulting with professionals and experts in the respective fields is recommended before using N-Cyclohexyltaurine in any specific application.