Products
Methylparaben
Synonyms:4-hydroxybenzoic acid methyl ester;methyl p-hydroxybenzoate;methyl-4-hydroxybenzoate;methylparaben;methylparaben, sodium salt;Nipagin
Chemical Property of Methylparaben
● Appearance/Colour:white crystalline powder
● Vapor Pressure:3.65E-05mmHg at 25°C
● Melting Point:125-128 °C(lit.)
● Refractive Index:1.4447 (estimate)
● Boiling Point:265.5 °C at 760 mmHg
● PKA:pKa 8.15(H2O,t =20.0) (Uncertain)
● Flash Point:116.4 °C
● PSA：46.53000
● Density:1.209 g/cm3
● LogP:1.17880
● Storage Temp.:0-6°C
● Solubility.:ethanol: soluble0.1M, clear, colorless
● Water Solubility.:Slightly soluble in water.
● XLogP3:2
● Hydrogen Bond Donor Count:1
● Hydrogen Bond Acceptor Count:3
● Rotatable Bond Count:2
● Exact Mass:152.047344113
● Heavy Atom Count:11
● Complexity:136
Safty Information
● Pictogram(s):
Xi,
Xn
● Hazard Codes:Xi,Xn
● Statements:36/37/38-20/21/22-36
● Safety Statements:26-36-24/25-39
Useful
Chemical Classes:Other Uses -> Preservatives
Canonical SMILES:COC(=O)C1=CC=C(C=C1)O
Uses:Methylparaben is the ester of methyl alcohol and p-hydroxybenzoic acid, It is a bacteriostatic agent and preservative that was added to local anesthetic agents without vasoconstrictors before 1984 to prevent bacterial growth.Allergic reactions developed from repeated exposures to parabens led to the removal of this agent from dental anesthetic solutions.Similar products produced by similar production methods, like ethyl p-hydroxybenzoate (paraben B) and propyl p-hydroxybenzoate (Nepalese c), are also disinfectant preservatives.The products are irritating to the skin. parabens is one of the most commonly used group of preservatives in the cosmetic, pharmaceutical, and food industries. Parabens provide bacteriostatic and fungistatic activity against a diverse number of organisms, and are considered safe for use in cosmetics, particularly in light of their low sensitizing potential. An evaluation of preservatives for use in leave-on cosmetic preparations lists parabens among the least sensitizing. The range of concentrations used in cosmetics varies between 0.03 and 0.30 percent, depending on the conditions for use and the product to which the paraben is added.Methylparaben is one of the most popular preservatives in beauty products and food items. According to the National Library of Medicine, the ingredient occurs naturally in a handful of fruits—like blueberries—though it can also be created synthetically.It's found in everything from cream cleansers and moisturizers to primers and foundations and helps these products maintain their effectiveness. Rabach says that it's chock-full of anti-fungal and antibacterial properties, which work wonders to extend the shelf life of skincare, haircare, and cosmetic products.
Methylparaben is an antimicrobial agent which is a white free-flowing powder. it is active against yeast and molds over a wide ph range. see parabens. Methyl 4-hydroxybenzoate is used as an anti-fungal agent. It is also used as a preservative in foods, beverages and cosmetics. It acts as an inhibitor of growth of molds and to lesser extent bacteria and as a vehicle for ophthalmic solution.
Detailed Introduction
Methylparaben is a preservative commonly used in the cosmetic and personal care industry. It is a member of the paraben family, which includes other preservatives like ethylparaben, propylparaben, and butylparaben.Here are some key points about methylparaben:
Preservation: Methylparaben is added to cosmetics and personal care products to prevent the growth and proliferation of microorganisms such as bacteria and fungi. It helps extend the shelf life of these products and maintain their quality and safety.
Safety: Methylparaben has been extensively studied and deemed safe for use in cosmetics and personal care products by regulatory bodies like the US Food and Drug Administration (FDA), the European Commission's Scientific Committee on Consumer Safety (SCCS), and the Cosmetic Ingredient Review (CIR) Expert Panel.
Wide Usage: Methylparaben can be found in a variety of products, including creams, lotions, shampoos, conditioners, makeup, deodorants, and sunscreens. It is widely used due to its effectiveness, stability, and compatibility with many cosmetic formulations.
Other Parabens: Methylparaben is often used in combination with other parabens (such as ethylparaben, propylparaben, and butylparaben) to provide a broader spectrum of antimicrobial protection.
Alternative Preservatives:In recent years, there has been increased consumer demand for preservative alternatives. As a response, some cosmetic companies have started using alternative preservatives or opting for preservative-free formulations. However, methylparaben remains a widely used and approved preservative within the industry.
It's important to note that while methylparaben has been extensively studied and deemed safe for use, some individuals may experience sensitivities or allergic reactions to it, just like with any other ingredient. If you have concerns or specific questions about cosmetic ingredients, it's best to consult with a dermatologist or healthcare professional.
Application
Methylparaben is primarily used as a preservative in various personal care, cosmetic, and pharmaceutical products. Its main purpose is to prevent the growth of bacteria, yeast, and mold, thereby extending the shelf life and ensuring the safety of these products. Here are some common applications of methylparaben:
Skincare products: Methylparaben can be found in moisturizers, cleansers, facial masks, toners, and other skincare products to maintain their quality and prevent microbial contamination.
Haircare products: Methylparaben is used in shampoos, conditioners, hair masks, and styling products to preserve their formula and inhibit the growth of microorganisms.
Body care products: Methylparaben is often added to body lotions, body washes, deodorants, and other personal care items to prevent spoilage and maintain product stability.
Makeup products: Methylparaben is commonly used in various types of cosmetics, including foundations, powders, eyeshadows, blushes, and lipsticks, to prevent the growth of bacteria and fungi.
Pharmaceutical products: Methylparaben can be present in oral suspensions, creams, ointments, and other pharmaceutical formulations as a preservative to ensure their safety and prevent contamination.
It's important to note that the use of methylparaben in products is regulated by authorities like the FDA (in the United States) and the European Commission in the EU. These agencies set concentration limits on the use of methylparaben and other preservatives to ensure product safety.
