Products
6-Amino-1-methyluracil
Synonyms:6-Amino-1-methyl-1H-pyrimidine-2,4-dione;2,4(1H,3H)-Pyrimidinedione,6-amino-1-methyl-;Uracil,6-amino-1-methyl- (7CI,8CI);1-Methyl-6-aminouracil;
Chemical Property of 6-Amino-1-methyluracil
● Appearance/Colour:almost white to slightly beige crystalline powder
● Melting Point:300 °C
● Refractive Index:1.548
● PKA:9.26±0.40(Predicted)
● PSA：80.88000
● Density:1.339 g/cm3
● LogP:-0.76300
● Storage Temp.:Keep in dark place,Inert atmosphere,Room temperature
● Solubility.:Soluble in diluted sodium hydroxide solution.
● XLogP3:-1.3
● Hydrogen Bond Donor Count:2
● Hydrogen Bond Acceptor Count:3
● Rotatable Bond Count:0
● Exact Mass:141.053826475
● Heavy Atom Count:10
● Complexity:221
Purity/Quality
99%, *data from raw suppliers
6-Amino-1-methyluracil *data from reagent suppliers
Safty Information
● Pictogram(s):
● Hazard Codes:Xn
● Statements:22-36/37/38
● Safety Statements:26
Useful
● Canonical SMILES: CN1C(=CC(=O)NC1=O)N
● Uses: 6-Amino-1-methyluracil is known to exert inhibitory effects towards DNA repair glycosylase. It is also known to be used as a flame retardant. 6-Amino-1-methyluracil may be used in the preparation of 1,1?-di methyl-1H-spiro[pyrimido[4,5-b]quinoline-5,5?-pyrrolo[2,3-d]pyrimidine]-2,2?,4,4?,6?(1?H,3H,3?H,7?H,1?H)-pentaone, via reaction with isatin in the presence of catalytic p-toluene sulfonic acid.
6-Amino-1-methyluracil, also known as Adenine or 6-Aminopurine, is an organic compound with the chemical formula C5H6N6O. It is a purine derivative and a component of nucleic acids. Adenine is one of the four nucleobases found in DNA and RNA, along with cytosine, guanine, and thymine (in DNA) or uracil (in RNA).Adenine plays a crucial role in cellular processes such as DNA replication and protein synthesis. It pairs with thymine (in DNA) or uracil (in RNA) through hydrogen bonding, forming one of the base pairs that make up the double helix structure of DNA.In addition to its role in nucleic acids, adenine is also involved in other biological processes. It serves as a component of cofactors such as NADH, NADPH, and FAD, which are involved in various enzymatic reactions. Adenine is also used in the synthesis of important molecules like ATP (adenosine triphosphate), which is known as the "energy currency" of the cell.Adenine can be obtained through various methods, including extraction from natural sources like fish intestines, or through organic synthesis. It is commercially available and widely used in scientific research, medical applications, and the pharmaceutical industry.When handling adenine, standard laboratory safety protocols should be followed, including wearing appropriate protective equipment and handling the compound in a well-ventilated area. It is also important to store adenine properly to prevent degradation and maintain its stability.
