Products
3,5-Dichloropentan-2-one
Synonyms:3,5-Dichloropentan-2-one;58371-98-5;2-Pentanone, 3,5-dichloro-;EINECS 261-227-0;3,5-dichloro-2-pentanone;SCHEMBL2407439;DTXSID70973934;AKOS006310527;EN300-708738
Chemical Property of 3,5-Dichloropentan-2-One
● Vapor Pressure:0.217mmHg at 25°C
● Refractive Index:1.444
● Boiling Point:208.1 °C at 760 mmHg
● Flash Point:82.3 °C
● PSA：17.07000
● Density:1.18 g/cm3
● LogP:1.81170
● XLogP3:1.6
● Hydrogen Bond Donor Count:0
● Hydrogen Bond Acceptor Count:1
● Rotatable Bond Count:3
● Exact Mass:153.9952203
● Heavy Atom Count:8
● Complexity:82.5
Safty Information
● Pictogram(s):
● Hazard Codes:
Useful
Canonical SMILES:CC(=O)C(CCCl)Cl
Detailed Introduction
3,5-Dichloropentan-2-one is a chemical compound with the molecular formula C5H8Cl2O. It is an organic compound that belongs to the group of ketones. The compound has a chlorine atom attached to the 3rd and 5th carbon atoms of the pentane chain, with a carbonyl (C=O) group on the 2nd carbon atom.
This compound is commonly used in organic synthesis and can be prepared through various methods, including the reaction of 3,5-dichloropentane with an oxidizing agent, such as potassium permanganate.3,5-Dichloropentan-2-one can have various applications in the chemical industry. It can be used as an intermediate in the synthesis of pharmaceuticals, agrochemicals, and other organic compounds. Additionally, it can also be used as a solvent or reagent in organic reactions and as a starting material for the synthesis of other derivatives.
It is important to handle this compound with care, following appropriate safety precautions, as it can be harmful if ingested, inhaled, or in contact with the skin or eyes.
Application
One potential application of 3,5-Dichloropentan-2-one is as a precursor in the synthesis of pyrrole derivatives, which are important building blocks in pharmaceutical and agrochemical development. Pyrroles have been found to possess various biological activities, including antimicrobial, antitumor, and anti-inflammatory properties.
3,5-Dichloropentan-2-one can undergo cyclization reactions with different amines, leading to the formation of pyrrole derivatives. These derivatives can then be further modified to create new molecules with desired properties for specific applications.
Additionally, 3,5-Dichloropentan-2-one can also be used as a starting material for the synthesis of other functionalized compounds, such as alcohols, esters, and amides, through various chemical transformations.It is important to note that proper handling and safety precautions should be followed when working with 3,5-Dichloropentan-2-one, as it is a potentially hazardous substance.
