Products
2,4-Diamino-6-hydroxypyrimidine
Hydroxypyrimidine Chemical Properties
| Melting point | 285-286 °C (dec.) (lit.) |
| Boiling point | 234.22°C (rough estimate) |
| density | 1.3659 (rough estimate) |
| refractive index | 1.7990 (estimate) |
| storage temp. | Keep in dark place,Inert atmosphere,Room temperature |
| solubility | DMSO (Slightly), Methanol (Slightly) |
| pka | 10.61±0.50(Predicted) |
| form | Fine Crystalline Powder |
| color | White to cream |
| Sensitive | Light Sensitive |
| Merck | 14,2981 |
| BRN | 125006 |
| InChIKey | SWELIMKTDYHAOY-UHFFFAOYSA-N |
| CAS DataBase Reference | 56-06-4(CAS DataBase Reference) |
| NIST Chemistry Reference | 4(1H)-pyrimidinone, 2,6-diamino-(56-06-4) |
| EPA Substance Registry System | 2,6-Diamino-4(1H)-pyrimidinone (56-06-4) |
Hydroxypyrimidine Product Description
2,4-Diamino-6-hydroxypyrimidine is a chemical compound with the molecular formula C4H6N4O. It is an organic compound belonging to the pyrimidine family. The compound has a pyrimidine ring structure, two amino groups (NH2) are connected at the 2-position and 4-position, and a hydroxyl group (OH) is connected at the 6-position. The chemical structure can be expressed as:Ammonia | | H--C--C--C--N--C--C--NH2 | |oh 2,4-Diamino-6-hydroxypyrimidine has various applications in the pharmaceutical industry. It is an important intermediate in the synthesis of many drugs, including antiviral and antitumor drugs. It is also used to produce several nucleotide analogs used in pharmaceutical research.
In addition to pharmaceutical applications, 2,4-diamino-6-hydroxypyrimidine is also used as an ingredient in agrochemicals. It is a key ingredient in the synthesis of plant growth regulators and fungicides. It is very important to follow a proper safety protocol when using 2,4-diamino-6-hydroxypyrimidine. Since it is classified as a chemical irritant, it should be handled with care and adequate personal protective equipment should be worn to avoid direct contact.
In summary, 2,4-diamino-6-hydroxypyrimidine is an organic compound with applications in pharmaceutical and agricultural fields. Its chemical structure makes it useful as an intermediate in the synthesis of pharmaceuticals and plant growth regulators.
Safety Information
| Hazard Codes | Xi |
| Risk Statements | 36/37/38 |
| Safety Statements | 22-24/25-36-26 |
| WGK Germany | 3 |
| Hazard Note | Irritant |
| TSCA | Yes |
| HS Code | 29335995 |
Hydroxypyrimidine Usage And Synthesis
| Description | 2,4-Diamino-6-hydroxypyrimidine (DAHP) is a selective, specific inhibitor of GTP cyclohydrolase I, the rate limiting step for de novo pterin synthesis. In HUVEC cells, the IC50 for inhibition of BH4 biosynthesis is about 0.3 mM. DAHP can be used to effectively block NO production in several cell types. |
| Chemical Properties | White Solid |
| Uses | 2,4-Diamino-6-hydroxypyrimidine (DAHP) is a selective, specific inhibitor of GTP cyclohydrolase I, the rate limiting step for de novo pterin synthesis. In HUVEC cells, the IC50 for inhibition of BH4 biosynthesis is about 0.3 mM. DAHP can be used to effectively block NO production in several cell types.[Cayman Chemical] |
| Uses | It stands at the beginning of the enzyme-catalyzed cascade that starts with this seven-carbon carbohydrate and ends with the aromatic amino acids phenylalanine, tyrosine, and tryptophan |
| Uses | 2,4-Diamino-6-hydroxypyrimidine (cas# 56-06-4) is a compound useful in organic synthesis. |
| Purification Methods | It recrystallises from H2O. [Beilstein 25 III/IV 3642.] |
