Products
2,4-Diamino-6-hydroxypyrimidine
Synonyms:4(1H)-Pyrimidinone,2,6-diamino- (8CI,9CI);2,4-Diamino-6-hydroxypyrimidine;2,4-Diamino-6-pyrimidinone;2,6-Diamino-3,4-dihydropyrimidin-4-one;2,6-Diamino-4(1H)-pyrimidinone;2,6-Diamino-4(3H)-pyrimidinone;2,6-Diamino-4-hydroxypyrimidine;2,6-Diamino-4-pyrimidinol;2,6-Diaminopyrimidin-4-one;2,6-Diaminopyrimidine-4(3H)-one;6-Aminoisocytosine;6-Hydroxy-2,4-pyrimidinediamine;NSC 44914;NSC 680818;NSC9302;
Chemical Property of 2,4-Diamino-6-hydroxypyrimidine
● Appearance/Colour:white solid
● Vapor Pressure:0.00232mmHg at 25°C
● Melting Point:285-286 °C (dec.)(lit.)
● Refractive Index:1.7990 (estimate)
● Boiling Point:288.5 °C at 760 mmHg
● PKA:10.61±0.50(Predicted)
● Flash Point:128.3 °C
● PSA：98.05000
● Density:1.84 g/cm3
● LogP:0.50900
● Storage Temp.:Desiccate at +4°C
● Sensitive.:Light Sensitive
● Solubility.:DMSO (Slightly), Methanol (Slightly)
Safty Information
● Pictogram(s):
Xi
● Hazard Codes:Xi
● Statements:36/37/38
● Safety Statements:22-24/25-36-26
Useful
● Description: 2,4-Diamino-6-hydroxypyrimidine (DAHP) is a selective, specific inhibitor of GTP cyclohydrolase I, the rate limiting step for de novo pterin synthesis. In HUVEC cells, the IC50 for inhibition of BH4 biosynthesis is about 0.3 mM. DAHP can be used to effectively block NO production in several cell types.
● Uses: 2,4-Diamino-6-hydroxypyrimidine (DAHP) is a selective, specific inhibitor of GTP cyclohydrolase I, the rate limiting step for de novo pterin synthesis. In HUVEC cells, the IC50 for inhibition of BH4 biosynthesis is about 0.3 mM. DAHP can be used to effectively block NO production in several cell types.[Cayman Chemical] It stands at the beginning of the enzyme-catalyzed cascade that starts with this seven-carbon carbohydrate and ends with the aromatic amino acids phenylalanine, tyrosine, and tryptophan 2,4-Diamino-6-hydroxypyrimidine (cas# 56-06-4) is a compound useful in organic synthesis.
2,4-Diamino-6-hydroxypyrimidine is a chemical compound with the molecular formula C4H6N4O. It is commonly used as an intermediate in the synthesis of various compounds, including pharmaceutical drugs and dyes.The compound has a pyrimidine ring structure consisting of two amino groups (NH2) and one hydroxyl group (OH) attached to different carbon atoms. This structure makes it a versatile building block for the synthesis of more complex molecules.2,4-Diamino-6-hydroxypyrimidine can be obtained by various synthetic methods, including the reaction of cyanamide with urea. It has several applications in the pharmaceutical industry, particularly in the synthesis of anticancer drugs and antibiotics.Overall, 2,4-Diamino-6-hydroxypyrimidine is an important compound that finds utility in various chemical and pharmaceutical applications.
Detailed Introduction
2,4-Diamino-6-hydroxypyrimidine is a chemical compound with the molecular formula C4H6N4O. It is an organic compound belonging to the pyrimidine family. The compound has a pyrimidine ring structure, two amino groups (NH2) are connected at the 2-position and 4-position, and a hydroxyl group (OH) is connected at the 6-position. The chemical structure can be expressed as:Ammonia | | H--C--C--C--N--C--C--NH2 | |oh 2,4-Diamino-6-hydroxypyrimidine has various applications in the pharmaceutical industry. It is an important intermediate in the synthesis of many drugs, including antiviral and antitumor drugs. It is also used to produce several nucleotide analogs used in pharmaceutical research.
In addition to pharmaceutical applications, 2,4-diamino-6-hydroxypyrimidine is also used as an ingredient in agrochemicals. It is a key ingredient in the synthesis of plant growth regulators and fungicides. It is very important to follow a proper safety protocol when using 2,4-diamino-6-hydroxypyrimidine. Since it is classified as a chemical irritant, it should be handled with care and adequate personal protective equipment should be worn to avoid direct contact.
In summary, 2,4-diamino-6-hydroxypyrimidine is an organic compound with applications in pharmaceutical and agricultural fields. Its chemical structure makes it useful as an intermediate in the synthesis of pharmaceuticals and plant growth regulators.
