Products
2-Amino-5-methylpyridine
Synonyms:(3-Trifluoromethylpyridin-2-yl)amine;3-(Trifluoromethyl)-2-pyridinamine;
Chemical Property of 2-Amino-5-methylpyridine
● Appearance/Colour:white or yellowish crystal
● Vapor Pressure:0.0794mmHg at 25°C
● Melting Point:76-77 °C(lit.)
● Refractive Index:1,524-1,528
● Boiling Point:226.999 °C at 760 mmHg
● PKA:pK1: 7.22(+1) (25°C)
● Flash Point:110.863 °C
● PSA：38.91000
● Density:1.068 g/cm3
● LogP:1.55340
● Storage Temp.:Refrigerator
● Sensitive.:Hygroscopic
● Solubility.:1000g/l
● XLogP3:1
● Hydrogen Bond Donor Count:1
● Hydrogen Bond Acceptor Count:2
● Rotatable Bond Count:0
● Exact Mass:108.068748264
● Heavy Atom Count:8
● Complexity:72.9
Purity/Quality
99% *data from raw suppliers
2-Amino-5-methylpyridine 98% *data from reagent suppliers
Safty Information
● Hazard Codes:T,Xi
● Statements:23/24/25-36/37/38-25
● Safety Statements:26-36/37/39-45-37/39-28A
Useful
● Canonical SMILES:CC1=CN=C(C=C1)N
● Uses：2-Amino-5-methylpyridine is a chemical compound with the molecular formula C6H8N2. It is a pyridine derivative that contains an amino group (-NH2) and a methyl group (-CH3) attached to the pyridine ring.This compound is often used as a building block or intermediate in organic synthesis for the preparation of various pharmaceuticals, agrochemicals, and dyes. It can also be used as a precursor for the synthesis of heterocyclic compounds.As with any chemical compound, it is important to follow proper safety protocols and consult reliable sources when working with or handling 2-Amino-5-methylpyridine.
Detailed Introduction
2-Amino-5-Methylpyridine, also known as 5-Methyl-2-aminopyridine or AMP, is a chemical compound with the molecular formula C₆H₈N₂. It belongs to the pyridine family of organic compounds and consists of a pyridine ring substituted with an amino group (-NH₂) at the 2-position and a methyl group (-CH₃) at the 5-position.
This compound is a colorless to pale yellow liquid with a characteristic odor. It is soluble in organic solvents such as ethanol and ether but has limited solubility in water.
2-Amino-5-Methylpyridine finds application in various fields. It is commonly used as a building block in organic synthesis, particularly in the pharmaceutical industry, for the synthesis of various compounds with biological activity. Its versatile structure allows for the introduction of different functional groups, making it a valuable intermediate in the production of pharmaceuticals, agrochemicals, and dyes.
Due to its basic properties, 2-Amino-5-Methylpyridine may also be used as a catalyst in various chemical reactions. It can act as a ligand in coordination chemistry and form complexes with metal ions.
It is important to handle this compound with caution, as it may be harmful if swallowed, inhaled, or absorbed through the skin. Proper protective equipment and handling procedures should be followed when working with 2-Amino-5-Methylpyridine.
Application
Here are some specific applications of 2-Amino-5-Methylpyridine:
Pharmaceutical industry: 2-Amino-5-Methylpyridine is used as a versatile intermediate for the synthesis of various pharmaceutical compounds. It can be used as a building block in the preparation of anti-inflammatory drugs, antihistamines, antifungal agents, and other medicinal compounds.
Agrochemical industry: This compound is used in the synthesis of pesticides, herbicides, and fungicides. It can be incorporated into these formulations to enhance their effectiveness against pests and diseases in crops.
Dyes and pigments: 2-Amino-5-Methylpyridine is employed as a precursor for the production of dyes and pigments. It can be converted into various colorants used in textiles, inks, paints, and coatings.
Photoinitiators: This compound can be utilized as a photoinitiator in the synthesis of UV-curable coatings, adhesives, and printing inks. Photoinitiators initiate crosslinking reactions upon exposure to UV light.
Polymer chemistry: 2-Amino-5-Methylpyridine is used as a monomer or crosslinker in the synthesis of polymeric materials. It can be utilized to introduce desired functionalities or improve the mechanical and thermal properties of the resultant polymers.
Coordination chemistry: This compound acts as a versatile ligand in coordination chemistry and can form complexes with various transition metal ions. These complexes find use in catalysts, sensors, and other applications.
It's essential to note that these applications are representative, and the compound may have additional uses that are specific to certain industries or research areas. Always consult safety data sheets and follow proper handling protocols when working with 2-Amino-5-Methylpyridine.
