Products
1,1,3,3-Tetramethylurea
Synonyms:1,1,3,3-tetramethylurea;tetramethylurea
Chemical Property of 1,1,3,3-Tetramethylurea
● Appearance/Colour:Clear colorless to pale yellow liquid
● Melting Point:-1 °C(lit.)
● Refractive Index:n20/D 1.451(lit.)
● Boiling Point:175.2 °C at 760 mmHg
● PKA:2.0(at 25℃)
● Flash Point:53.9 °C
● PSA：23.55000
● Density:0.9879 g/cm3
● LogP:0.22960
● Storage Temp.:Store below +30°C.
● Solubility.:H2O: 1 M at 20 °C, miscible
● Water Solubility.:miscible
● XLogP3:0.2
● Hydrogen Bond Donor Count:0
● Hydrogen Bond Acceptor Count:1
● Rotatable Bond Count:0
● Exact Mass:116.094963011
● Heavy Atom Count:8
● Complexity:78.4
Purity/Quality
99% *data from raw suppliers
Tetramethylurea *data from reagent suppliers
Safety Information
● Pictogram(s):
Xn
● Hazard Codes:Xn,T
● Statements:22-61
● Safety Statements:53-45
Useful
● Chemical Classes:Nitrogen Compounds -> Urea Compounds
● Canonical SMILES:CN(C)C(=O)N(C)C
● Uses: Tetramethylurea is used as a solvent in dyestuff industries, in condensation reaction and intermediates in surfactant. It is utilized for base catalyzed isomerization and alkylation hydrocyanation due to its low permittivity. It reacts with oxalyl chloride to prepare tetramethyl chloroformamidinium chloride, which is used for the conversion of carboxylic acids and dialkyl phosphates to anhydrides and pyrophosphates respectively.
1,1,3,3-Tetramethylurea, also known as TMU or N,N,N',N'-tetramethylurea, is a chemical compound with the molecular formula C6H14N2O. It is a crystalline solid that is highly soluble in water and other polar solvents.TMU is widely used as a solvent and a reagent in various chemical reactions. Its high solubility and low toxicity make it a preferred solvent in applications such as extraction processes, catalysis, and as a reaction medium for organic synthesis. It can also be used to dissolve organic compounds that are less soluble in other solvents.Similar to other urea derivatives, TMU can act as a hydrogen bond donor and acceptor, which makes it useful in a variety of chemical transformations. It is commonly employed in peptide synthesis, metal-catalyzed reactions, and as a reaction medium in pharmaceutical research.
