Products
1-Bromo-2-butyne
Synonyms:2-Butyne,bromo- (6CI,7CI);1-Bromo-2-butyne;1-Bromo-3-methyl-2-butyne;2-Butyn-1-ylbromide;2-Butynyl bromide;4-Bromobut-2-yne;
Chemical Property of 1-Bromo-2-butyne
● Appearance/Colour:Clear pale yellow-greenish liquid
● Vapor Pressure:15.2mmHg at 25°C
● Refractive Index:n20/D 1.508(lit.)
● Boiling Point:124.7 °C at 760 mmHg
● Flash Point:36.3 °C
● PSA：0.00000
● Density:1.46 g/cm3
● LogP:1.40460
● Storage Temp.:Flammables area
● Solubility.:Miscible with acetonitrile.
● XLogP3:1.6
● Hydrogen Bond Donor Count:0
● Hydrogen Bond Acceptor Count:0
● Rotatable Bond Count:0
● Exact Mass:131.95746
● Heavy Atom Count:5
● Complexity:62.2
Purity/Quality
99%min *data from raw suppliers
1-Bromo-2-butyne *data from reagent suppliers
Safty Information
● Pictogram(s):R10:;
● Hazard Codes:R10:;
● Statements:10
● Safety Statements:16-24/25
MSDS Files
Useful
● Canonical SMILES: CC#CCBr
● Uses: 1-Bromo-2-butyne is used in the preparation of six to eight annulated ring compounds in reaction with indoles and pseudopterane (+/-)-Kallolide B, which is a marine natural product. Further, it acts as a precursor in the preparation of axially chiral teranyl compounds, alkylation of L-tryptophan methyl ester, 4-butynyloxybenzene sulfonyl chloride and mono-propargylated diene derivative. In addition to this, it is also used in the synthesis of isopropylbut-2-ynylamine, allenylcyclobutanol derivatives, allyl-[4-(but-2-ynyloxy)phenyl]sulfane, allenylindium and axially chiral teranyl compounds.
1-Bromo-2-butyne, also known as 1-bromo-2-butene or bromobutene, is an organic compound with the molecular formula C4H5Br. It is a colorless liquid that is primarily used as a reagent in organic synthesis.1-Bromo-2-butyne is often utilized in organic reactions to introduce the bromine atom into various molecules. Its reactivity as an electrophile makes it useful in the preparation of other organic compounds, such as pharmaceuticals, agrochemicals, and natural products.In addition to its chemical synthesis applications, 1-bromo-2-butyne is also used in research and development efforts. Its unique reactivity and ability to undergo various reactions, such as substitution, addition, and elimination reactions, make it valuable for studying reaction mechanisms and developing new synthetic methodologies.However, it is important to note that 1-bromo-2-butyne can be hazardous and should be handled with care. It is highly flammable and may cause irritation or burns upon contact with skin or eyes. Proper safety precautions, such as wearing protective equipment and working in a well-ventilated area, should be followed when handling this compound.
